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Michael DR et al

Over-the-counter antacids like calcium carbonate or magnesium hydroxide are generally safe to use alongside semaglutide to manage indigestion

Most of the reported side effects are related to gastrointestinal problems such as nausea, vomiting, diarrhea, stomach paralysis, and constipation

Weight loss during this week is still not likely to be huge, as clinical trials have proven that people lose an average of less than 1% per week of their starting body weight in the early stages

Other factors that may increase infection risk in diabetes patients include: Immunosuppressive effects of poorly controlled hyperglycemia Neuropathy leading to reduced sensation and delayed recognition of infections Vascular complications impairing tissue perfusion and immune cell delivery Frequent antibiotic use for other infections, disrupting normal flora Obesity , which is common in type 2 diabetes and creates skin folds prone to moisture and fungal growth Conversely, medications that improve glycemic control, including GLP-1 receptor agonists and tirzepatide, generally reduce infection risk by normalizing the metabolic environment

This means the gene mutation happened randomly in their lifetime