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Monitor potassium levels in patients at risk for hypokalemia, if indicated (e.g., patients using potassium-lowering medications, patients taking medications sensitive to serum potassium concentrations)

A drinking-in-the-dark procedure was used to test the effects of semaglutide on binge-like drinking in male and female mice

INS-1 832/3 cells (a gift from Prof Christopher Newgard, Duke University) (Hohmeier et al ., 2000) were maintained in RPMI at 11 mM glucose, supplemented with 10% FBS, 10 mM HEPES, 1 mM pyruvate, 1 mM pyruvate, 50 M -mercaptoethanol and 1% penicillin/streptomycin

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Control mice with weight loss matching that of mice receiving 1 mg/kg liraglutide were not protected from atherosclerosis, suggesting that liraglutide has weight lossindependent anti-atherogenic effects

Indeed, a phase 2 mechanistic trial (NCT05936151) investigating change in eGFR from baseline to week 24 with multiple doses of retatrutide vs