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Credit: Joanna Sadowska, PhD, EMBA !

Conclusion GLP-1 RA therapy has a respiratory safety profile that is neither uniformly benign nor hazardous, stratified by mechanism, agent subclass, and clinical context

Key differences between Tirzepatide (Mounjaro) and Semaglutide (Ozempic) for type 2 diabetes and weight loss

While challenges with adherence, side effects, and weight regain upon discontinuation have prompted the search for additional strategies, targets like GLP-1R, GIPR, and GDF8 (Myostatin) still remain the most highly relevant and active areas of research for developing effective obesity treatments

Combination users were matched, in a 1:1 ratio, to patients prescribed the same background drug, duration of background drug, and time conditional propensity score

Results At week 4 after discontinuation, compared with the control group, AOM treatment still had weight loss effect (WMD=0.32 kg, 95% CI3.602.97, P=0.85, I2=83%)