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Kiyosue A

Importantly, these medications carry a boxed warning about thyroid C-cell tumors observed in rodent studies and are contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

At that point, weight was still declining the curve had not plateaued, suggesting even greater reductions may be possible with longer treatment

Semaglutide as Ozempic and liraglutide as Victoza are licensed for type 2 diabetes management, while semaglutide as Wegovy and liraglutide as Saxenda are specifically licensed for weight management

Contemporary classification of glucagon-like peptide 1 receptor agonists (GLP1RAs)

Although approved for type 2 diabetes, Ozempic became widely associated with the broader GLP-1 boom because of its impact on body weight and metabolic outcomes