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Future innovations will build on this foundation, offering even better tools for managing obesity and metabolic disease

Mazdutide is not approved for human use by the FDA or any regulatory agency

Early data shows improvements in cardiovascular risk markers (cholesterol, blood pressure, inflammation), but these are surrogate endpoints, not proven event reduction

Average weight loss was about 15% of body weight

Many patients find that switching to semaglutide monotherapy provides superior, durable weight loss without phentermine's stimulant side effects (jitteriness, insomnia, elevated blood pressure)

The results at 25% MACE highlight some CV benefit from this drug, while those at 50% of MACE only demonstrated non-inferiority vs