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In dedicated renal outcome trials, SGLT2 inhibitors significantly reduced the risk of composite renal adverse events, including the development of ESKD or renal replacement therapy, which led to the positioning of SGLT2 inhibitors as the mainstay of chronic kidney disease management

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Substance use and cessation have complex associations with obesity, with overlapping brain pathways with food reward and disordered eating [178,186]

These drugs work in several ways, including: Encouraging insulin release from the pancreas in response to food