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RCTs evaluating GLP-1 RA have not identified indicators of suicidality
Eli Lilly's orforglipron, a second type of GLP-1 pill, is still completing phase three trials, with results expected in the first quarter of 2026

46.Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: design and baseline characteristics of SOUL, a randomized trial
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