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The randomised, double-blind, placebo-controlled study enrolled 2,339 adults with obesity or overweight and at least one weight-related health condition (such as high blood pressure or heart disease) but without diabetes

A pooled comparative efficacy analysis showing tirzepatide outperforms semaglutide on body weight reduction regardless of study design [6]

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The HbA1c reductions reported in the phase 2 diabetes trial are comparable in magnitude to those reported for dedicated diabetes medications

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