glp-1/glp-2 dual agonist GLP-1/GIP | Tirzepatide | Obesity & T2DM Mx | Harrison's Update(22nd Ed.) Trends in the Development of

P., vorm Walde, T

Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Rossing P, Kolkhof P, Nowack C, Schloemer P, Joseph A, et al

This underscores the uncertainty surrounding the long-term effects of these agents, which patients may need to take indefinitely to sustain weight loss

Patients with certain genetic variants may respond more strongly to semaglutide monotherapy, while others benefit from dual-pathway activation using tirzepatide or GLP-Squared combinations

An MRI-based exploratory analysis also indicated that cotadutide significantly reduced hepatic fat compared to placebo [84]

But Mounjaro (tirzepatide) consistently shows the strongest results