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In the present study, we speculate that the primary pathway through which GS supplementation improves dyslipidemia in hyperglycemic rats is mainly through enhanced hepatic signaling of insulin depicted by the increased transcriptional activity of Irs1 and Irs2 genes (Figure 7A)

Diabetes care 35, 21212127 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Ghorbani Z, Hekmatdoost A, and Mirmiran P (2014) Anti-hyperglycemic and insulin sensitizer effects of turmeric and its principle constituent curcumin