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Description
As central insulin resistance appears to be a risk factor for neurodegenerative disorders, these analogues might provide interesting avenues to protect against neurodegeneration and conditions such as Alzheimers and Parkinsons disease

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Dosing protocols are the same for men and women

Discussion In individuals with type 2 diabetes in whom diabetes was inadequately managed by GLP-1 RA therapy with or without additional oral glucose-lowering medications, once-weekly IcoSema demonstrated statistical superiority to semaglutide 1.0 mg with respect to HbA 1c reduction from baseline to week 52
