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This specific 8:3 ratio is intentional

Effects were attenuated in GPR84-deficient mice, confirming the receptor dependency

| Concentration | BAC Water | Doses at 1.0mg | Doses at 2.4mg | |---------------|-----------|----------------|----------------| | 5mg/mL | 4.0mL | 20 doses | ~8 doses | | 2.5mg/mL | 8.0mL | 20 doses | ~8 doses | **Note:** At 4mL+ of liquid, ensure you have a large enough syringe (5mL or two separate 3mL draws) to transfer all the BAC water accurately

However, cotadutide demonstrated superior performance in decreasing liver triglyceride levels and ameliorating mitochondrial functional markers in the liver compared to liraglutide, despite comparable reductions in body weight and food intake between the two treatments [43]

Because adipose tissue is metabolically active in ways that affect reproductive hormones