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Due to its pharmacokinetic profile, SEM presents a slightly different toxicity profile when compared to other GLP-1 receptor agonists, such as less frequent injection site effects and hypoglycemic risk (that can further increase when associated with insulin or sulfonylureas), but also more frequent vomiting [9]

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Allergy 66(8):989998 Wilson RH, Whitehead GS, Nakano H et al (2009) Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness[J]