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(2025) [40], were conducted in adults with obesity (typically BMI 30 kg/m 2 ), most of whom had comorbid type 2 diabetes and consistently excluded individuals with active, severe, or unstable psychiatric disorders

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Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants

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