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La dcouverte du GLP-1 : du laboratoire la rvolution mdicale Le GLP-1 a t identifi au dbut des annes 1980, dans le sillage des recherches sur les hormones intestinales

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Hypersensitivity reactions to tirzepatide, including anaphylaxis, have been reported in the FDA prescribing information

Because GLP1R expression was most prevalent at later stages of prostate cancer progression (metastases, CRPC, NEPC), the clinical implications of targeting GLP1R signaling alone or combination with standard-of-care therapies are of significant interest
34 More research in the context of obesity is needed
