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Identifying molecular or imaging biomarkers in this patient population could facilitate earlier diagnosis, enable targeted interventions, and support the monitoring of disease progression
Traditional blockbusters (biologics for oncology or immunology) still lead in aggregate revenue

The protein DPP-4 is localized to a small pocket known as the catalytic pocket, which has serine at position 630
Regular monitoring and follow-up are essential components of safe, effective treatment

doi: 10.1016/j.cmet.2015.07.009 [DOI] [PMC free article] [PubMed] [Google Scholar] 11

DPP4 Inhibition A well-established family of oral hypoglycemic medications for the treatment of T2DM is gliptins, a kind of DPP4 inhibitor (Figure 1)
