short term use of glp 1 GLP-1 receptor agonists GLP-1 for Diabetes vs GLP-1

Both groups were adjusted for baseline differences using propensity score weighting (eTable 1 in Supplement 1), so differences at follow-up could be attributed to the treatment

Several GLP-1 agonists created to treat type II diabetes are now commonly prescribed off-label for weight loss

This is a mechanism no approved drug currently uses Phase 2 trials showed up to 24% body weight reduction over 48 weeks, meaningfully exceeding tirzepatide and semaglutide outcomes Phase 3 trials are currently underway

doi: 10.1056/NEJMe020054 80 OkabeKMatsushimaSIkedaSIkedaMIshikitaATadokoroTet al

Personalized nutrition goals take away the guesswork about getting enough protein when appetite is low

E., DAlessio, D