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These findings indicate that the protective effects of GLP-1RAs may involve shared molecular mechanismssuch as the AMPK/SIRT1 signaling pathwaywhile also exhibiting disease-specific regulation

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However, the dedicated HF trials were not designed to address atherosclerotic CVD outcomes

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2011;155A(9):21122124

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*Correspondence: Li Luo, [email protected]

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Circulation 148 , 16061635 (2023)

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