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If weight remains stable for another four to six weeks, further reduction may be possible

The medications contain the same active compounds (semaglutide or tirzepatide) in comparable formulations

UK adults who have a Body Mass Index (BMI) of 30 or above, or between 27 and 30 with at least one weight-related comorbidity, may now be prescribed the drugs in pill format rather than the previously available injectables

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Combining different treatment modalities (including lifestyle interventions, pharmacotherapies and bariatric surgery) may support people to achieve individualised long-term goals, maximise health benefits and improve quality of life
