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placebo (p<0.001), the effect was greatest in subjects with eGFR>60 ml/min/1.73 m2

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Nicola Magrini, Unit head for Innovation, Evidence synthesis and Clinical research, University Hospital, Bologna, Italy, Co-Chair of the Guidelines Development GroupComments: GLP-1 and inclusion in the essential medicineMr Deus Mubangizi, Director, Medicines and Health Products Policies and Standards Department, WHOPanel discussionMs Jeanette Hunter General Primary Health Care at the National Department of Health (NDoH) of South Africa, and Co-Chair of the Guidelines Development Group