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Methods Databases were searched for randomized controlled trials (RCTs), casecontrol, cohort and observational studies involving use of GLP1RA in the intervention arm post-bariatric surgery

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Although dedicated trials of GLP-1RAs in AITD are lacking, preliminary reports suggest potential impacton thyroid volume, thyroid function, and autoimmune activity

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How GLP-1 Works: GLP-1 is a natural gut hormone that helps you feel full and supports metabolism

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Electronic databases including PubMed, Embase, and Web of Science were searched from inception until August 2025 using keywords such as GLP-1 receptor agonist, diabetic retinopathy, glaucoma, age-related macular degeneration, ocular disease, and neuroprotection. The search focused on identifying preclinical studies, large-scale retrospective cohort studies, and post-hoc analyses of major clinical trials that evaluated the utility and potential mechanisms of GLP-1RAs in ophthalmic diseases

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