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Considering application, the market is divided into cardiovascular, oncology, and others

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, The weight loss curve showed no sign of plateauing at 80 weeks

Published Phase 2 effect sizes most prominently the ~24 percent mean body weight reduction at the 12 mg dose tier in the obesity Phase 2 (PMID 37366315) exceed those reported for dual or single agonists at comparable durations, an outcome that researchers attribute to the additional glucagon-arm contribution to body-composition and energy-expenditure pathways