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In patients with type 2 diabetes inadequately controlled on metformin alone, the overall incidence of adverse reactions of hypoglycemia was 1.3% in patients given add-on sitagliptin and 2.1% in patients given add-on placebo

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Research published in Neuropsychopharmacology confirmed this pathway, demonstrating that the sleep-promoting effects of glycine are mediated specifically through these receptors

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