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The most common exclusion criteria included major depressive disorder, uncontrolled hypertension, malignant neoplasms and liver disease, with the latter for tirzepatide only

Developing new ways to treat these patients is of the utmost importance, explained study senior author Dr

13, 25 May 2022, www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.889923/full

Conditions such as hypothyroidism, polycystic ovary syndrome (PCOS), insulin resistance, and hormonal imbalances often contribute to weight gain or make weight loss more challenging

These effects can be replicated through the intraperitoneal administration of Exendin-4 in the Sal + Ex-4 group
