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Over time, some of these agents (in particular, GLP-1 agonists and SGLT2 inhibitors), which were initially developed for their glucose-lowering actions, have demonstrated significant beneficial pleiotropic effects, thus expanding their potential therapeutic applications

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Furthermore, increased CRP levels explained part of the elevated risk of COVID-19related mortality with age, specifically in the absence of obesity and impaired metabolic health

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Comparative efficacy, safety, and cardiovascular outcomes with once-weekly subcutaneous semaglutide in the treatment of type 2 diabetes: Insights from the SUSTAIN 17 trials

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It is also important to understand that implementing such tests in routine clinical practice is not uniform in different countries due to issues such as cost, accessibility, reimbursement, and non-recommendation in guidelines

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This is about the same price as other brand-name GLP-1 receptor agonists like Ozempic (semaglutide), Victoza (liraglutide), and Mounjaro (tirzepatide)

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Farr, O

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