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Over time, some of these agents (in particular, GLP-1 agonists and SGLT2 inhibitors), which were initially developed for their glucose-lowering actions, have demonstrated significant beneficial pleiotropic effects, thus expanding their potential therapeutic applications

Furthermore, increased CRP levels explained part of the elevated risk of COVID-19related mortality with age, specifically in the absence of obesity and impaired metabolic health

Comparative efficacy, safety, and cardiovascular outcomes with once-weekly subcutaneous semaglutide in the treatment of type 2 diabetes: Insights from the SUSTAIN 17 trials

It is also important to understand that implementing such tests in routine clinical practice is not uniform in different countries due to issues such as cost, accessibility, reimbursement, and non-recommendation in guidelines

This is about the same price as other brand-name GLP-1 receptor agonists like Ozempic (semaglutide), Victoza (liraglutide), and Mounjaro (tirzepatide)

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