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Description
These agents indirectly influence the CA1 region of the ventral hippocampus, thereby modulating hunger and satiety, as well as emotional responses to food, which are implicated in BEDs (BED) [23]

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If orforglipron is approved along with Novo Nordisk's oral Wegovy (see Oral Wegovy), there will be two oral GLP-1 therapies available in 2026

The foundation is simple: protein first for satiety, muscle protection, and recovery

Angiotensin II Receptor Blockers (ARBs) Mechanism: Block Angiotensin II receptors vasodilation, aldosterone Examples: Losartan, Valsartan, Olmesartan Key Points: Alternative for patients who cannot tolerate ACE inhibitors (e.g., cough) 6

However, for diabetes treatment purposes, these drugs must have a prolonged duration of action
