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[29] found a modest but significant reduction in headache risk with tirzepatide: by 24 months, the risk of having headaches was ~ 20% lower in the tirzepatide group compared to controls (RR 0.803, 95% CI 0.6680.966)

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Improved biological activity of Gly2- and Ser2-substituted analogues of glucose-dependent insulinotrophic polypeptide

[DOI] [PubMed] [Google Scholar] 36

Ben attributes this to several factors: Proven effectiveness in clinical trials and real-world use Social media and press coverage showcasing dramatic weight loss stories Advances in drug delivery, including long-acting formulations and oral options Expanding indications beyond diabetes to include obesity treatment Were in a situation where its the right molecule at the right time, Ben notes