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Subcutaneous route leads with 64% share, while oral formulations expand quickly with rising preference for non-invasive therapies

[26] showed that liraglutide-dependent weight loss relies on its binding to GLP-1Rs located mainly in POMC/CART (cocaine- and amphetamine-regulated transcript) anorexigenic neurons in the ARC, but an indirect inhibitory effect of agouti-related peptide (AgRP) orexigenic neurons via -aminobutyric acid (GABA)-ergic signaling was also observed

Treatment with Mounjaro (tirzepatide) can lead to a rapid improvement in blood sugar (glucose) levels which may cause blurry vision or temporarily worsen diabetic retinopathy (DR) - a condition that affects the blood vessels in the retina

6 Clinical evidence unveils the translational potential of GLP-1RAs GLP-1RAs notably lower the risk of cirrhosis and HCC in individuals with type 2 diabetes and liver conditions