can semaglutide mess with your hormones Cause Infertility? Evidence and Guidance Does Semaglutide Affect Your Period?

6 mmol/l)-induced glucagon secretion

Amongst SGLT2-I, canagliflozin specifically has raised concerns about risk of bone fracture, although it is unclear whether an association exists with other SGLT2-I

Similarly, the SELECT cardiovascular outcome trial, which followed over 17,000 patients with obesity but without diabetes for more than three years, found no significant elevation in cancer rates among semaglutide users

The SURPASS-CVOT trial, published in the New England Journal of Medicine in December 2025, studied over 13,000 people with type 2 diabetes and existing heart disease over a median of four years

These are the most common Wegovy side effects, but a complete list is available in the Patient Information Leaflet

Youve got to have fat, Caliendo says