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Simply drinking plain water may not be enough if the diarrhea is frequent

When food moves more slowly through the intestines, there may be increased opportunity for bacterial fermentation of undigested carbohydrates in the colon, potentially leading to greater gas production

NIH National Library of Medicine, National center for biotechnology information

They copied exendin-4 in the lab, made a few chemical tweaks so it would be safe for humans, and called the drug exenatide

Efficacy We found that GLP-1s have a significant impact on weight loss and managing HbA1c, but the magnitude of the effects varied for GLP-1 users as compared to controls based on whether patients were diagnosed with type 2 diabetes only, obesity or overweight only, or both type 2 diabetes and obesity or overweight/obesity

Some patients experienced even greater weight reduction with long-term consistency and lifestyle support