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Inhibiting phosphatidylinositol-3 kinase (PI3K) and ERK1/2 reduced HG's effects

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GLP-1 medications bind to GLP-1 receptors in special cells in the pancreas called pancreatic beta cells
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These findings suggest GLP-1 receptor agonists may help reduce substance use and substance-related harms across alcohol, opioid, and tobacco use disorders
