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Fatigue and Muscle Weakness Semaglutide can sometimes cause fatigue, which may feel like a general lack of energy or muscle weakness

Every-other-week dosing would result in subtherapeutic levels and poor outcomes

The criteria for inclusion consisted of meeting the Diagnostic and Statistical Manual of Mental Disorders , fifth edition (DSM-5) criteria for current PTSD with a symptom duration of 6 months at screening (as assessed with the Mini International Neuropsychiatric Interview (MINI) for DSM-5), and a CAPS-5 total severity score of 35 at baseline

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In both trials, there was no difference in rates of nonfatal myocardial infarction and cardiovascular death between GLP-1 RA treated patients and placebo
