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La Nota AIFA 100 nasce per definire criteri di prescrivibilit e rimborsabilit SSN di varie classi di farmaci nel diabete tipo 2 e include anche i doppi agonisti GIP/GLP-1 come tirzepatide

Tirzepatide, marketed under the brand name Mounjaro, is a prescription medicine primarily used to improve blood sugar levels in adults with type 2 diabetes

These efforts have led to the development of various GLP-1 receptor agonists, the most recent being semaglutide and tirzepatide, approved for the treatment of type 2 diabetes in 2018 and 2022, respectively

While both cause similar issues, semaglutide shows slightly lower rates of gastrointestinal problems in clinical trials
