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Biotin: Essential for energy production and macronutrient metabolism

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Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

A government program that subsidizes the copay for millions of potential patients is a clean test of that thesis, even shared with Novo

Study characteristics The included studies were published between 2016 and 2025, with sample sizes ranging from 3,183 to 17,604 participants

There are still some criteria that need to be met