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Clinical guidelines still recommend naltrexone or acamprosate as first-line treatment, with the best evidence for reducing heavy-drinking days

State drug utilization data

Some patients report less nausea when injecting during eating windows, while others tolerate injection fine during fasts

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* Despite the ability of #GLP-1s to produce significant #weightreduction and related health benefits, challenges such as GI side effects, risk of nutrient inadequacies, #loss of #muscle and #bone mass, high costs, frequent discontinuation, and #weightregain limit the use of these drugs for #longterm #success in individuals and populations

For Mounjaro-related adverse effects, the appropriate external cause code is Y42.3 (Insulin and oral hypoglycaemic [antidiabetic] drugs causing adverse effects in therapeutic use)