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This is mediated by its abilities to increase insulin secretion while inhibiting glucagon

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.ClinicalTrials

The percentages of individuals who had a substantial weight reduction of 5% or more were 85%, 89%, and 91% with tirzepatide 5 mg, 10 mg, and 15 mg, respectively

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Tirzepatide Half-Life Explained Tirzepatide has an average half-life of about 5 days
