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Top-Selling Medicines in 2025 H1: GLP-1 in the New Drug Vanguard The first half of 2025 saw GLP-1-based therapies cement their status among the worlds highest-grossing drugs

Ozempic dosing schedule: Weeks 1-4: Starting dose 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1 mg once weekly Weeks 13-16: 2 mg once weekly Wegovy Wegovy is FDA-approved for weight management alongside diet and exercise in people with obesity, or people who have overweight and other weight-related health conditions

GLP-1 medications are only one part of the weight loss solution

Medical guidance is also essential for people experiencing side effects or managing conditions such as pregnancy, pancreatitis, or thyroid-related risks 7

The treatment is part of a holistic medical weight management strategy, which includes lifestyle and dietary modifications to maximize the effectiveness of the medication and support long-term health improvement