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The label notes, In Zepbound clinical trials, hair loss was reported more frequently in female than male patients in the Zepbound (7.1% female versus 0.5% male) and placebo (1.3% female versus 0% male) treatment groups. Treatments for hair loss Experts say telogen effluvium with GLP-1 use is typically temporary, but people who develop hair loss should seek medical evaluation

To prevent such adverse effects, studies have identified factors such as age, gender, the number of concurrent oral medications, and a history of gastrointestinal diseases as risk factors for GLP-1RA-induced gastrointestinal side effects

The Semaglutide Treatment on Coronary Plaque Progression (STOP) trial (NCT03985384) used serial coronary computed tomography angiography (CCTA) to explore the effect of subcutaneous semaglutide on coronary plaque progression in patients with T2DM who had established ASCVD or at least one additional CVD risk factor [113]

Mark Mallon, Anthony Rodgers, the George Medicines team, and Brandon Capital investors, Stephen Thompson and Melissa Byrne

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The food passage stimulates the release of gut hormones, and water shifts from the bloodstream into the intestines leading to bloating, diarrhea, hypotension, tachycardia, and reactive hypoglycemia due to the exaggerated release of insulin