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Strengthening primary health care systems encourages earlier identification of metabolic risks and expands access to evidence-based treatments before severe complications develop

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In a randomized, single-blind, 24-week study, participants assigned to dual therapy of 2 mg weekly of the GLP-1 receptor agonist exenatide (Bydureon, AstraZeneca) and 10 mg daily of the SGLT2 inhibitor dapagliflozin (Farxiga, AstraZeneca) lost more weight than those taking either agent alone or those receiving dapagliflozin and metformin extended-release (Xigduo XL, AstraZeneca) or phentermine/topiramate extended-release (Qsymia, Vivus)

These findings are similar to previous studies where the percentage of total calories was 44.5, 36.4, and 17.1% carbohydrates, fat, and protein (22)

Yang, R

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