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Because it is a very powerful drug and it would be a shame if we gave up on it because the side effects were bad in the first week or two and we didn't find a way to persist

Drug Interactions 7.1 Monoamine Oxidase Inhibitors (MAOI) Concomitant use of MAOIs and bupropion is contraindicated

15 The dose of this product is also based on the insulin component in units, and the recommended starting dose is dependent on the patients background therapy at the time of drug initiation

Notice I said should

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