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On September 19, 2025, the FDA issued Import Alert 66-80, which authorizes field staff to detain without physical examination shipments of GLP-1 active pharmaceutical ingredients (APIs) from manufacturers not included on its newly established Green List.[1] This action follows FDAs September 5 th announcement of the Green List initiative to curb illegal imports of semaglutide, tirzepatide, and other corresponding APIs.[2] Together, the Green List and Import Alert form FDAs most aggressive enforcement measures to date against GLP-1 imports

However, their use raises important clinical considerations

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Smart intake approaches involve using optimized, intuitive systems that have been designed to capture safety data directly from reporters in structured formats, eliminating subsequent manual data entry while also ensuring appropriate routing between adverse event and product complaint pathways (e.g