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The other arrived more recently as a weekly injection promising weight loss, blood sugar control, and heart health

Emphasize a long-term perspective and gradual, sustainable improvements

Patients with existing heart or kidney disease may benefit from starting SGLT-2 inhibitors therapy, while those with a higher risk of developing these conditions, such as obese patients and those with no cardiogenic stroke, may benefit more from GLP-1 RAs

Aardvark Therapeutics ARD-101 Aardvarks lead candidate, oral ARD-101 , is a potent pan-agonist of bitter taste receptors (TAS2R) that stimulates enteroendocrine cells in the digestive tract, triggering the release of gut-peptide hormones like GLP-1 and cholecystokinin (CCK), a satiety hormone that activates gut-brain signaling to regulate hunger

The drugs sole target is the GLP-1 pathway, which has a major role in blood sugar regulation and appetite cues

Legislative Activity Across Key States Discussions about how to govern and test insurance models began gaining momentum around 2020 and 2021, and several states are now taking concrete steps to address fairness in pricing