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Systemic doses of exendin-4 (2.4 30.0 g/kg) have been shown to reduce the locomotor activating effects of cocaine [113, 115]

These signs require immediate medical assessment

Second, the jump from 8 mg to 12 mg produced only 1 percent additional benefit

Patients experiencing new neurological symptoms should report them to their healthcare provider and consider reporting to FDA MedWatch

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