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Odds of gastrointestinal events were similar between tirzepatide and GLP-1 RAs, except for diarrhoea with tirzepatide 10 mg (OR 1.51 [95% CI 1.07, 2.15], I 2 0%) (Table 2)

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Understanding the risk of gallstones is essential for semaglutide users

You will need to be monitored closely during pregnancy.

Both medications have demonstrated safety profiles across multi-year clinical trials
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