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After matching, both cohorts consisted of 6329 patients each

Retatrutide Phase 2 trial New England Journal of Medicine Peer-reviewed Phase 2 trial data on retatrutide in adults with obesity

Multi-dose vials (5 mL) are more common because they provide enough medication for several weeks of injections at various dose levels, which reduces the number of vials you need and can lower overall costs

Gastrointestinal slowdown from GLP-1 agonists may theoretically affect how the body absorbs oral contraceptives, making this a critical conversation with your healthcare provider before starting treatment

The FDA's review focused exclusively on adults 50 and older

Avoid extreme caloric restriction Maintain a moderate caloric deficit of about 500-750 calories per day