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doi: 10.1097/MD.0000000000035394 68 RajagopalSAlruwailiFMavratsasVSernaMKMurthyVLRajiM

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Inadequate dosing may occur when patients remain on subtherapeutic doses due to side effect concerns or insurance coverage limitations

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2 Interactions between the GLP-1 pathway and alcohol As shown in Figure 1, the accumulated preclinical findings imply that the GLP-1 pathway modulates alcohol-mediated responses, which include the following: 1) alcohol drinking, 2) alcohol-induced behaviors and neurochemistry, 3) the motivation to consume alcohol and alcohol-seeking, and 4) relapse drinking

For muscle cramping, clinicians should first assess for electrolyte abnormalities, including magnesium, calcium, and potassium, before considering supplementation