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In terms of cytokines, IL-17A, which is a strong activator of neutrophils (80), is significantly increased by obesity, and is associated with exacerbation of the pathophysiological factors of asthma in humans and mice (75, 76, 78, 81)

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N Engl J Med 2023;389:106984

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Knudsen LB, Nielsen PF, Huusfeldt PO, Johansen NL, Madsen K, Pedersen FZ, et al

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