glp 1 agonists for diabetes Glucagon-like peptide-1 (GLP-1) receptor are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 mellitus and #obesity. GLP-1 receptor agonists and GLP-1 and glucose-dependent insulinotropic GLP-1 receptor agonists | How
Description
10 (2016): 14641473, 10.1001/jamainternmed.2016.1522
Psychol Sport Exerc
Incretins are gut-derived peptide hormones, primarily GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), secreted after nutrient intake to enhance glucose-dependent insulin release from pancreatic cells
By decreasing gastric emptying, they also reduce post-meal glucose spikes, which is attractive for diabetes and weight management treatment. These drugs work differently from traditional weight loss medications: They modulate appetite and hunger suppression rather than stimulating the nervous system to increase calorie burn
Interestingly, the plasma concentration achieved with once-weekly exenatide ER is comparable to that of a single injection of immediate-release exenatide (Byetta) [60, 61]
Livesey G, Taylor R, Livesey HF, Buyken AE, Jenkins DJA, Augustin LSA, et al
