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Stronger inverse associations were seen among older men (70 years) (ITT HR 0.56
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Petrelintide, a long-acting amylin analog, is being tested in Phase II trials and may offer improved tolerability and sustained weight loss.
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Lactation remains under-studied, but small datasets found no detectable semaglutide in milk samples (with a modeled max relative infant dose) and similarly no quantifiable tirzepatide in sampled milk
