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Moreover, glucagon treatment in human hepatocytes leads to the downregulation of CYP gene expression, and the underlying mechanism may be driven by the activation of glucagon receptors expressed in the liver.125,207,208 Drugs targeting both GLP-1 and glucagon receptors are currently under development, and it is vital to examine their indirect effects on CYP gene expression

Lexapro, a selective serotonin reuptake inhibitor, targets depression and anxiety , while Wegovy, a GLP-1 receptor agonist, focuses on weight loss and blood sugar regulation

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Scientific World Journal

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